Metabolism Diazepam is N-demethylated by CYP3A4 and 2C19 towards the active metabolite N-desmethyldiazepam, and it is hydroxylated by CYP3A4 to your Lively metabolite temazepam. Observe neonates subjected to diazepam in the course of pregnancy or labor for signs of sedation and watch neonates

The history hazard of significant delivery defects and miscarriage with the indicated inhabitants is unidentified. All pregnancies Possess a track record threat of start defect, loss, or other adverse outcomes. When you have been making use of benzodiazepines for your shorter period of time,